Is your skincare just not working? Let your DNA decide your routine!

BY MADELYN CHIN

Have you ever wondered why the skincare products that seem to work for your friends do nothing for your skin? Instead of spending a fortune trying numerous products recommended by internet articles and influencers, try taking a cheek swab and mailing it off—the skincare regimen that’s sent back to you may very well be the answer you’ve been looking for.

This process is critical to the field of cosmetogenomics, a branch of genetics that combines DNA analysis and dermatology to create personalized skin treatments for each user. 

What is cosmetogenomics?

Cosmetogenomics explores the relationship between genetic makeup and complexion, personalizing beauty habits to what is most beneficial to one’s specific skin type; it tends to mainly focus on anti-aging.

Studies have found that genetics plays a large role in numerous aspects of external appearances. For example, genomic variations, such as Single Nucleotide Polymorphisms (SNPs), can have implications for the risk of an individual developing common diseases and conditions—these variations are responsible for the diversity of genetic identities in a population. Therefore, the detection of certain mutations (or lack thereof) can help researchers find individualized treatments for consumers, based on the risks of specific skin and health conditions.

DNA-based Skincare

DNA-based skincare is becoming more and more appealing because of its precise analysis, which delivers more long-term benefits than generic skincare. Some emerging brands include Anake, EpigenCare, Genetic Beauty, Pure Culture Beauty, Caligenix, Dermatype, and Imagene Labs. 

Nearly all brands use a DNA test to generate the consumer’s genetic profile. Companies then analyze different aspects of the genetic makeup, such as epigenetic markers, to determine how the consumer’s skin health may be affected by specific skincare ingredients and environmental factors. Some major results companies tend to target are decreased collagen degradation, decreased oxidative stress, and decreased skin inflammation. Companies are able to determine products that stimulate these processes based on how well the consumer’s skin would be able to fight specific stressors related to these factors.

Beyond this internal analysis, many brands also use a lifestyle analysis to grasp how external factors affect an individual’s skin type. The combination of these tests allows consumers to be recommended both personalized products as well as specific lifestyle changes in order for them to reach their desired skin goals. 

Some brands, such as EpigenCare, Caligenix, and Dermatype, also use Artificial Intelligence as a way to virtually analyze existing external skin features and to create formulas for individualized profiles.

As this skincare approach is becoming popular, it is important to recognize it is largely inaccessible due to how expensive it is. The high price is not only due to the use of advanced technology and complex testing, but also because the products provided based on the genetic test are produced in limited quantities, resulting in the need for repurchasing for continued use. Additionally, many consumers are still skeptical of using this method because of its complex process and the potential misuse of genetic information. 

Cosmetogenomics has the potential to completely alter the way skincare is approached, moving away from the current “one-size-fits-all” model. While the most precise technology is still being developed, cosmetogenomics offers a promising intersection between genetics and skincare that would increase precision and innovation.

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DNA-Based Skincare Personalization - Cosmetogenomics. (2025, April 30). Stellarix.  https://stellarix.com/insights/articles/dna-based-skincare-personalization/

Perbal, B. & Gabaron, S. (2021). Mastering health: liberating beauty: Will the cosmetics of tomorrow be genetic? Journal of Cell Communication and Signaling, 15(4):483-490. https://doi.org/10.1007/s12079-021-00656-w. 

Upadhyay, A. (2024, October 28). Cosmetogenomics: Revolutionizing Personalized Skincare. Microbe Investigations Switzerland. https://microbe-investigations.com/what-is-cosmetogenomics/.